Description
MOTS-C Research:
98-99% Purity HPLC
MOTS-c is a mitochondrial-derived peptide composed of 16 amino acids. It is naturally produced in the mitochondria and plays a vital role in regulating metabolism, energy production, and cellular stress responses. Because of its impact on metabolic balance, MOTS-c is actively studied in relation to aging, weight management, insulin sensitivity, and exercise performance.
Unlike most peptides synthesized in the nucleus, MOTS-c is unique because it originates from mitochondrial DNA, giving it a central role in the body’s cellular energy regulation systems.
Reported Benefits and Uses
1. Metabolic Regulation
MOTS-c has been shown in studies to enhance glucose metabolism and improve insulin sensitivity, making it highly relevant in obesity, type 2 diabetes, and metabolic syndrome research. It may help support more stable blood sugar levels and energy use.
2. Fat Loss and Weight Management
By promoting efficient energy metabolism, MOTS-c may support fat loss and body composition improvement. It may help the body shift toward using fat as an energy source, particularly during times of metabolic stress such as fasting or exercise.
3. Increased Exercise Endurance
Some research suggests MOTS-c can boost endurance and physical performance by enhancing mitochondrial function and improving muscle energy utilization. This effect may support recovery, stamina, and overall physical capacity.
4. Anti-Aging and Longevity Potential
MOTS-c is being explored for its anti-aging potential, especially due to its role in activating AMPK, a key energy sensor in cells. AMPK activation is associated with increased lifespan, improved cellular repair, and reduced inflammation.
5. Cellular Protection and Stress Resilience
MOTS-c appears to improve the body’s ability to resist oxidative and metabolic stress, supporting cellular function and protecting against damage caused by poor diet, aging, or environmental factors.
Mechanism of Action
MOTS-c works by activating AMP-activated protein kinase (AMPK), a critical regulator of cellular energy homeostasis. When activated, AMPK increases the uptake and utilization of glucose and fatty acids, helping the body use energy more efficiently and adapt to physical or metabolic stress.
MOTS-c’s activity in skeletal muscle also plays a role in its performance-enhancing and fat-burning effects. It supports mitochondrial function, which is central to energy production, endurance, and cellular health.
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Key Information: Peptides are not recognized as dietary supplements. Research chemicals are defined as substances used by researchers for medical and scientific study. These chemicals are meant for laboratory research use only and are not for human or veterinary application. This clear distinction is indicated on the labels of research chemicals, exempting them from specific regulations under Title 21, Parts 100-740 of the Code of Federal Regulations (21CFR).
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